منابع مشابه
Clozapine augmentation with amisulpride.
A 42-year-old man with treatmentresistant schizophrenia presented a progressive clinical worsening under clozapine treatment (450 mg/d). He experienced worsening auditory hallucinations, increased distress and decreased working and social functioning (Positive and Negative Syndrome Scale [PANSS] score 97; positive subscale 21; negative subscale 31; general subscale 45). He experienced several s...
متن کاملAugmentation of Clozapine With Amisulpride in Patients With Treatment-Resistant Schizophrenia An Open Clinical Study
Background: Therapeutic options for patients with treatment-resistant schizophrenia are limited. In such cases, a combination of atypical antipsychotic drugs is an often used strategy. We tested the hypothesis that the combination of amisulpride and clozapine would lead to long-term improvement in this patient group. Objective: 15 patients with treatment-resistant schizophrenia participated in ...
متن کاملAmisulpride Augmentation for Clozapine-Refractory Positive Symptoms: Additional Benefit in Reducing Hypersialorrhea
One-third to half of patients taking clozapine suffer from refractory symptoms despite adequate treatment. Among other adverse effects, clozapine-induced hypersalivation (CIH) occurs in approximately half of all patients. This is a case of a 30-year-old male with refractory schizophrenia; in this patient, the remission of residual positive symptoms, as well as the reduction of CIH, was achieved...
متن کاملClozapine resistance: augmentation strategies.
BACKGROUND Clozapine (CLZ) is not effective in more than 50% of treatment-resistant schizophrenic patients. In these cases, several pharmacological strategies are used in clinical practice, with different levels of evidence for both safety and efficacy. OBJECTIVES In the present paper we critically reviewed literature data regarding the efficacy and safety of adjunctive agents in CLZ-resistan...
متن کاملRisperidone Augmentation of Clozapine
Sir, Henderson and Goff (1996) in an open trial reported augmentation of clozapine's effect with risperidone in schizophrenic patients not responding to clozapine alone. There are no reports in literature of controlled trials or on long term effectiveness of this combination. In this report a case has been described which shows the long term effectiveness of this combination in resistant schizo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Psychiatry & Neuroscience
سال: 2014
ISSN: 1180-4882
DOI: 10.1503/jpn.140094